Ronald Ghossein Selected Research

prolinedithiocarbamate (PDTC)

9/2020	Poorly differentiated thyroid carcinoma.
1/2019	Poorly Differentiated Carcinoma of the Thyroid Gland: Current Status and Future Prospects.
11/2016	Clinicopathologic Features of Fatal Non-Anaplastic Follicular Cell-Derived Thyroid Carcinomas.
9/2016	Genomic Landscape of poorly Differentiated and Anaplastic Thyroid Carcinoma.
3/2016	Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers.
12/2015	Undetectable Thyroglobulin Levels in Poorly Differentiated Thyroid Carcinoma Patients Free of Macroscopic Disease After Initial Treatment: Are They Useful?
11/2015	NF2 Loss Promotes Oncogenic RAS-Induced Thyroid Cancers via YAP-Dependent Transactivation of RAS Proteins and Sensitizes Them to MEK Inhibition.
8/2013	Poorly differentiated thyroid carcinoma presenting with gross extrathyroidal extension: 1986-2009 Memorial Sloan-Kettering Cancer Center experience.
12/2006	Patterns of expression of cell cycle/apoptosis genes along the spectrum of thyroid carcinoma progression.

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Ronald Ghossein Research Topics

Disease

38	Neoplasms (Cancer) 01/2022 - 01/2002
26	Thyroid Neoplasms (Thyroid Cancer) 01/2022 - 11/2002
20	Carcinoma (Carcinomatosis) 01/2022 - 01/2002
14	Neoplasm Metastasis (Metastasis) 01/2022 - 10/2004
8	Papillary Thyroid Cancer 01/2021 - 12/2004
6	Anaplastic Thyroid Carcinoma 01/2022 - 12/2006
4	Pleomorphic Adenoma 01/2022 - 07/2015
4	Disease Progression 01/2021 - 04/2016
3	Melanoma (Melanoma, Malignant) 11/2019 - 10/2004
3	Necrosis 01/2019 - 07/2015
3	Carcinogenesis 01/2018 - 11/2007
2	Head and Neck Neoplasms (Head and Neck Cancer) 01/2019 - 11/2017
2	Adenoid Cystic Carcinoma (Cylindroma) 10/2017 - 07/2006
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2014 - 05/2004
1	Thyroid Nodule (Nodule, Thyroid) 01/2022
1	Follicular Adenocarcinoma 01/2022
1	Lymphatic Metastasis 12/2020
1	Thrombosis (Thrombus) 12/2020
1	Testicular Neoplasms (Testicular Cancer) 11/2019
1	Myoepithelioma 01/2019
1	Papillary Thyroid Microcarcinoma 01/2018
1	Salivary Gland Neoplasms (Salivary Gland Cancer) 10/2017
1	Adenocarcinoma 01/2015
1	Hepatocellular Carcinoma (Hepatoma) 11/2012
1	Fibrosis (Cirrhosis) 05/2010
1	Inflammation (Inflammations) 05/2010
1	Tongue Neoplasms (Tongue Neoplasm) 01/2009
1	Glandular and Epithelial Neoplasms (Neoplasms, Glandular) 02/2008
1	Oligodendroglioma 11/2007
1	Medullary Carcinoma 09/2006
1	Familial medullary thyroid carcinoma 09/2006
1	Adenoma (Adenomas) 01/2002

Drug/Important Bio-Agent (IBA)

9	prolinedithiocarbamate (PDTC)IBA 09/2020 - 12/2006
6	IodineIBA 01/2022 - 11/2008
4	5'-N-methylcarboxamideadenosineIBA 01/2019 - 01/2015
4	Proteins (Proteins, Gene)FDA Link 01/2018 - 11/2007
4	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2018 - 01/2011
3	ParaffinIBA 12/2020 - 01/2002
3	Messenger RNA (mRNA)IBA 01/2014 - 05/2004
2	VemurafenibIBA 01/2022 - 01/2018
2	Mitochondrial DNA (mtDNA)IBA 01/2022 - 01/2019
2	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 10/2019
2	Transcription Factors (Transcription Factor)IBA 01/2021 - 02/2008
2	ChromatinIBA 01/2021 - 10/2017
2	Immune Checkpoint InhibitorsIBA 11/2019 - 01/2019
2	AntigensIBA 11/2019 - 01/2019
2	1,2-didecanoyl-3-phosphatidic acid (PA(10))IBA 01/2019 - 01/2015
2	Thyroglobulin FDA Link 12/2015 - 12/2004
2	Oncogene Proteins (Oncogene Protein)IBA 12/2011 - 01/2011
2	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 01/2011 - 12/2004
2	OligonucleotidesIBA 01/2009 - 04/2005
2	CyclinsIBA 11/2007 - 01/2002
1	NAD (NADH)IBA 01/2022
1	RacivirIBA 01/2022
1	tremelimumabIBA 01/2022
1	MTOR InhibitorsIBA 01/2022
1	Lysine (L-Lysine)FDA Link 01/2022
1	durvalumabIBA 01/2022
1	RNA (Ribonucleic Acid)IBA 01/2022
1	Citric Acid (Citrate)FDA LinkGeneric 01/2022
1	Cyclin A2IBA 01/2022
1	Capsules (Microcapsules)IBA 12/2020
1	FibrinIBA 12/2020
1	EPTCIBA 12/2019
1	Androgen Receptors (Androgen Receptor)IBA 11/2019
1	VaccinesIBA 11/2019
1	Hepatitis B e AntigensIBA 11/2019
1	Formaldehyde (Formol)FDA Link 10/2019
1	Peptide Initiation Factors (Initiation Factor)IBA 01/2019
1	CrizotinibIBA 01/2018
1	tipifarnib (R115777)IBA 01/2018
1	Nonsense Codon (Nonsense Mutation)IBA 01/2018
1	Pharmaceutical PreparationsIBA 01/2018
1	2- (4- (3- quinolin- 6- ylmethyl- 3H- (1,2,3)triazolo(4,5- b)pyrazin- 5- yl)pyrazol- 1- yl)ethanolIBA 01/2018
1	Phosphotransferases (Kinase)IBA 01/2018
1	RO5126766IBA 01/2018
1	Apoptosis Regulatory ProteinsIBA 11/2017
1	N-acetyltalosaminuronic acid (NAT)IBA 10/2017
1	Neurofibromin 2 (Merlin)IBA 11/2015
1	ras ProteinsIBA 11/2015
1	CateninsIBA 05/2013
1	Irinotecan (Camptosar)FDA LinkGeneric 11/2012
1	alvocidib (flavopiridol)IBA 11/2012
1	Doxycycline (Periostat)FDA LinkGeneric 12/2011
1	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2010
1	AntibodiesIBA 02/2008
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 11/2007
1	Small Interfering RNA (siRNA)IBA 10/2006
1	Calcitonin (Calcitonin, Eel)FDA LinkGeneric 09/2006
1	Thyrotropin Alfa FDA LinkGeneric 12/2004
1	Monophenol Monooxygenase (Tyrosinase)IBA 10/2004
1	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 10/2004
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 05/2004

Therapy/Procedure

19	Therapeutics 01/2022 - 07/2006
7	Thyroidectomy 01/2020 - 11/2002
3	Radiotherapy 01/2022 - 09/2015
3	Drug Therapy (Chemotherapy) 10/2020 - 04/2016
1	Immunotherapy 01/2019
1	Molecular Targeted Therapy 04/2016
1	Laryngectomy 07/2006